| COS Unique Id: |
100610 |
| Title: |
Vision Grant |
| Sponsor: |
Society of Critical Care Medicine (SCCM)
|
| Sponsor Type: |
Professional Society or Association |
| Deadline: |
September 4, 2008
|
| Upper Amount: |
$50,000 |
| Amount Note: |
The maximum level of funding is $50,000 per year.
Grant recipients will be announced at the Society of Critical Care
Medicine's Convocation and Award Ceremony at the Critical Care Congress. |
| Eligibility: |
The principal investigator must be a current SCCM
member and maintain SCCM membership through the life of the grant.
Applications are encouraged from both established and junior
investigators from all critical care disciplines. Applications from
junior investigators (defined as Assistant Professor or below) may be a
request for independent support or may include a research mentor who is
also an SCCM member and who demonstrates strong research credentials in
the areas of clinical and outcomes research.
To be eligible for the Vision Grant, the applicant may not apply for five years if they were a previous winner. |
| Citizenship or Residency: |
Unrestricted
|
| Activity Location: |
Unrestricted
|
| Requirements: |
Ph.D./M.D./Other Professional
|
| Abstract: |
SCCM, in collaboration with the Critical Care
Education and Research Foundation (CCERF), announces the availability
for grant support for SCCM members focused on clinical and outcomes
research specifically related to the Society's four goals and
objectives: 1. Education (Learn It) 2. Integrated Team of Dedicated Experts (Deliver It) 3. Outcomes Measurements and Reporting (Measure It) 4. Continuous Improvement (Improve It)
SCCM
seeks to sponsor research efforts that will ultimately improve patient
care in the intensive care unit (ICU). Investigator-initiated research
should help expand and advance the understanding of clinical outcomes
specifically related to these goals.
SCCM's interest is broad.
For example, the society encourages applications that focus on
technical aspects, such as electronic surveillance systems, yet
similarly encourage studies exploring cultural and educational factors
among ICU staff that either impede or facilitate a climate promoting
best practice and error reduction. SCCM will give priority to projects
that have broad relevance. As one extension of this, single center
projects, for example, should specifically address the potential to
generalize their findings to other critical care settings.
Grant recipients will also be required to submit an abstract for blind review for presentation at SCCM Annual Congress. |
| Contact Name: |
Trish Glover |
| Contact Address: |
Society of Critical Care Medicine 500 Midway Drive |
| Contact City: |
Mount Prospect |
| Contact State: |
Illinois |
| Contact Zip: |
60056 |
| Contact Country: |
United States |
| Contact Phone: |
     +1 (847) 493-6440 |
| Contact Email: |
pglover@sccm.org |
| URL for more information: |
http://www.sccm.org/Membership/Grants/Pages/VisionGrant.aspx |
| Date Last Revised: |
April 24, 2008 |
| URL from COS to Bookmark this record: |
http://fundingopps.cos.com/cgi-bin/getRec?id=100610 |
| Keywords: |
Critical Care
Patient Care and Education
Patient Care Management
|
| Funding Type: |
Research
|
| COS Unique Id: |
105169 |
| Title: |
Major Grants |
| Sponsor: |
PepsiCo Foundation
|
| Sponsor Type: |
Private Foundation |
| Deadline: |
September 15, 2008
|
| Amount Note: |
Requests over $100,000 are accepted. |
| Eligibility: |
Applicant organizations must be tax-exempt as
defined under section 501 (c)(3) of the Internal Revenue Code. While
the Foundation generally prefers to invest in local U.S. communities
where PepsiCo has a presence, it also funds international programs.
Typically, PepsiCo Foundation chooses to work with academic and
community organizations where there are established relationships. |
| Citizenship or Residency: |
Unrestricted
|
| Activity Location: |
Unrestricted
|
| Requirements: |
Nonprofit Academic Institution
|
| Abstract: |
PepsiCo Foundation is the primary charitable arm of
PepsiCo, Inc. and has a long history of and commitment to corporate
citizenship, demonstrating PepsiCo's core value of caring for the
communities in which its employees live and work.
The PepsiCo Foundation focuses its grant making in the following areas: 1.
The Foundation's mission in Health and Wellness is to advance the
knowledge about how to encourage healthy lifestyles and effect positive
behavior change. Initiatives of particular interest are those which
address one or more of the following focus areas: a. Community Activation b.Minority Communities c.Health Professionals
2.
PepsiCo Foundation's mission in Diversity and Inclusion is to support
education and community organizations which advance opportunities in
three core areas: 1.Undergraduate and graduate education, skill development and economic mobility 2. Women- and minority-owned business 3. Workplace equality
Specifically,
the Foundation provides support to a select number of colleges and
universities which provide opportunities for individuals of all
backgrounds to gain leadership skills and experience. Programs at the
high school level with an emphasis on skill development for students of
color and students from low-income households also receive Foundation
support. The Foundation also considers organizations which help foster
a positive environment for minority-owned and women-owned businesses as
well as workplace climate for gay, lesbian, bisexual and transgender
communities.
3. The Foundation's mission around the Environment
is to advance the knowledge and methods of water resource management
which are sustainable and positively impact both quantity and quality
of water supply in developing nations.
4. Under the Thought
Leadership initiative, the Foundation supports organizations and
research initiatives which help to address issues critical to the
betterment of society. |
| Contact Name: |
Director, Corporate Contributions |
| Contact Address: |
PepsiCo, Inc. 700 Anderson Hill Road |
| Contact City: |
Purchase |
| Contact State: |
New York |
| Contact Zip: |
10577 |
| Contact Country: |
United States |
| Contact Phone: |
     +1 (914) 253-2000 |
| URL for more information: |
http://www.pepsico.com/PEP_Citizenship/Contributions/GrantGuidelines/index.cfm |
| Date Last Revised: |
April 24, 2008 |
| URL from COS to Bookmark this record: |
http://fundingopps.cos.com/cgi-bin/getRec?id=105169 |
| Keywords: |
Behavior Modification
Community Development or Revitalization
Community or Outreach Programs
Community Services
Cultural Diversity
Environmental Sciences
Health and Medicine
Health Behavior
Health Promotion
Minority Health
Natural Resources Management
Water Quality
Water Supply
|
| Funding Type: |
Program or Curriculum Development or Provision
|
| COS Unique Id: |
112751 |
| Title: |
Methods for Prevention Packages Program (MP3) (R01) |
| Sponsor: |
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
|
| Sponsor Type: |
Federal, U.S. |
| Deadline: |
August 25, 2008
|
| Deadline Note: |
An optional letter of intent is due July 25, 2008. This opportunity expires August 26, 2008.
Renewal and resubmission applications are not permitted in response to this FOA. |
| Upper Amount: |
$2,400,000 |
| Amount Note: |
This FOA will utilize the NIH Research Project
Grant (R01) award mechanism. The NIAID intends to award up to $4
million in FY 2009 to fund four to six applications submitted in
response to this FOA. NIMH is also providing $500,000 in support of
this FOA. Applicants may request a project period of up to four years
and a budget of up to $600,000 in direct costs in each year, plus
applicable facilities and administrative costs.
This program does not require cost sharing. |
| Eligibility: |
Applications may be submitted by domestic or
foreign, for-profit or nonprofit organizations and public or private
institutions, such as universities, colleges, hospitals, and
laboratories; units of state and local governments; eligible agencies
of the federal government; and faith-based or community-based
organizations. |
| Citizenship or Residency: |
Unrestricted
|
| Activity Location: |
Unrestricted
|
| Requirements: |
Small Business Ph.D./M.D./Other Professional Commercial Government Nonprofit Academic Institution
|
| Abstract: |
The National Institute of Allergy and Infectious
Diseases (NIAID) and the National Institute of Mental Health (NIMH)
invite applications for multidisciplinary research programs that - devise optimal HIV prevention packages (combination interventions) for specific populations; - design clinical studies to rigorously examine the safety and efficacy of these "packages" in the target population; and -
perform pilot studies to demonstrate that the proposed prevention
package is acceptable to the target population and the study design is
appropriate and feasible.
This FOA is intended to encourage
collaborations between behavioral and biomedical clinical scientists,
epidemiologists, mathematical modelers, and clinical trial design
specialists.
It is expected that teams conducting this research
will perform a systematic review and meta-analysis of existing
prevention research data germane to the target population(s) chosen.
These data can be used to develop a mathematical model to assess the
impact of various combinations of interventions which have been shown
to reduce HIV incidence in the same or similar settings.
If
mathematical modeling is performed, sensitivity analyses showing how
the outcome is influenced by key risk behaviors and other variables
should be provided. The impact of incomplete adherence, risk
compensation, and other behavioral factors should also be considered. A
full discussion of the key assumptions of the mathematical model should
be provided.
Sensitivity analyses showing how the outcome is
influenced by key risk behaviors and other variables (e.g., stage of
the epidemic, dominant modes of transmission in the population,
proportion of persons in major risk groups, etc., as appropriate)
should be provided. The impact of incomplete adherence, risk
compensation, and other behavioral factors should also be considered. A
full discussion of the key assumptions of the mathematical model should
be provided.
The prevention packages should include both
biomedical and behavioral interventions that can be applied in a
complementary manner in the target population. As indicated,
interventions to optimize adherence and minimize disinhibition (risk
compensation) should be included. The population selected may be a
specific high-risk group, such as African American men who have sex
with men (MSM) or injection drug users in Eastern Europe; a nation as a
whole, such as the population of Thailand, with its specific
combination of risk groups, risk behaviors, and incidence rates; or a
region, such as southern Africa. Selection of populations that are most
affected by the epidemic in a given setting (e.g., women and youth in
South Africa) is strongly encouraged.
The team should carefully
examine the strengths and limitations of the research design chosen to
evaluate the proposed prevention package(s), making comparisons with
alternative designs. The control intervention should include HIV risk
reduction counseling, free condoms, and other behavioral and biomedical
interventions considered standard of care.
Finally, the team
should (a) perform a pilot study to demonstrate that the proposed
prevention package is acceptable to the target population, and (b)
present convincing evidence that the research design proposed is
feasible operationally and will provide a conclusive assessment of the
prevention package's safety and efficacy. The latter should include
evidence that sufficient HIV incidence events will occur in the
proposed setting, sample population, and follow-up period. A phase 1
clinical study may be adequate to demonstrate that the prevention
package is acceptable to the target population. Applicants are
encouraged to discuss the scope of the pilot study with NIAID program
staff prior to submission. |
| Contact Name: |
Lisa Scott-Morring, M.S. |
| Contact Address: |
Division of Extramural Activities Room 2232, MSC-7614 6700B Rockledge Drive |
| Contact City: |
Bethesda |
| Contact State: |
Maryland |
| Contact Zip: |
20892-7614 |
| Contact Country: |
United States |
| Contact Phone: |
     +1 (301) 451-3697 |
| Contact Fax: |
+1 (301) 493-0597 |
| Contact Email: |
ScottLi@niaid.nih.gov |
| URL for more information: |
http://grants1.nih.gov/grants/guide/rfa-files/RFA-AI-08-044.html |
| Date Last Revised: |
April 24, 2008 |
| URL from COS to Bookmark this record: |
http://fundingopps.cos.com/cgi-bin/getRec?id=112751 |
| Keywords: |
HIV Prevention
|
| Sponsor Reference No: |
RFA-AI-08-044 |
| Funding Type: |
Collaboration or Cooperative Agreement
Research
|
| COS Unique Id: |
113584 |
| Title: |
PHASE II Comprehensive ICOHRTA AIDS/TB (U2R) |
| Sponsor: |
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
|
| Sponsor Type: |
Federal, U.S. |
| Deadline: |
August 18, 2008 August 18, 2009
|
| Deadline Note: |
Non-required letters of intent are due July 19, 2008, and July 18, 2009. This opportunity will expire on August 19, 2009.
Internal coordination required.
Only one application for a Phase II Comprehensive ICOHRTA AIDS TB award
will be allowed from any foreign institution in response to this FOA.
In situations in which more than one planning grant has been awarded to
institutions in close proximity in the same country, applicants will be
strongly encouraged to submit a single, integrated application for a
Phase II award. Only one Phase II award will be made to any foreign
institution in the ICOHRTA AIDS TB program. |
| Amount Note: |
This FOA will utilize the International Training
Cooperative Agreement (U2R) grant mechanism. The estimated amount of
funds available for support of five to six new or renewal Research
Training Units awarded as a result of this announcement is $3,000,000
for fiscal year 2009. Future year amounts will depend on annual
appropriations. Facilities and administrative costs are limited to 8
percent for all awards and sub-awards.
Each new Phase II
ICOHRTA AIDS TB applicant in a Research Training Unit may request a
project period of up to five years and a budget for direct costs up to
$275,000 dollars for the first year. The Phase II Comprehensive
ICOHRTA-AIDS/TB applicants that comprise the Research Training Unit may
request up to $550,000 in combined direct costs for each year. In the
first budget year, the foreign institution's direct cost budget must be
at a direct cost level equal to or greater than its linked partner
institution's. The foreign institution's direct cost budget may
increase in years two through five to reflect the increased capacity of
the foreign applicant to facilitate training and research. The foreign
institution's direct cost budget may exceed $275,000 in years two
through five, but the combined direct costs each year for the Research
Training Unit (two linked awards) may not exceed $550,000.
Applicants
in a renewal Phase II ICOHRTA AIDS TB Research Training Unit may each
submit an application requesting a project period of up to five years
and a combined budget of up to $550,000 in direct costs for each year.
The direct cost budget for the foreign institution applicant in the
Research Training Unit should be at least 60 percent of the combined
budget. Alternatively, the foreign institution in the renewal Research
Training Unit may submit one application for the Research Training Unit
in which the U.S. partner(s) are funded through a sub-award. In this
situation, the budget submitted on the application may not exceed
$550,000 in direct costs for each year and the combined sub-awards to
any U.S. institutions should not exceed 40 percent of the requested
budget.
This program does not require cost sharing. |
| Eligibility: |
Eligible applicants include institutions of higher education, nonprofits, and non-domestic organizations.
New
applications for a Phase II Comprehensive ICOHRTA-AIDS/TB Award will
only be accepted from foreign institutions that were awarded a planning
grant under a Phase I ICOHRTA-AIDS/TB program competition and the U.S.
nonprofit partner institution that the planning grant recipient has
chosen. The foreign and U.S. partner applicant institutions must have
achieved a strong record of receiving or being significantly involved
in HIV/AIDS and/or TB international research. Both the foreign and U.S.
partner institutions must demonstrate the capacity and leadership
necessary for the successful implementation and long-term productivity
of the program. Renewal applications will only be accepted from
existing ICOHRTA AIDS TB recipients.
The PD in a new Phase II
application from the foreign institution is expected to be the PD from
the Phase I award. Any changes in PD in renewal applications of a
Research Training Unit need to be well-justified. Both the foreign and
U.S. partner PDs must be directly involved in and funded to do research
in resource-poor settings and there must be tangible evidence of very
strong linkage to that ongoing research as collaborating partners. The
PDs must hold faculty or other long-term research positions at a public
or private nonprofit research institution that will allow them adequate
time and provide appropriate facilities, salary support and resources,
including access to patients or patient data, when necessary.
To
a limited extent and with prior FIC approval, U.S. trainees will be
eligible for foreign research experience under this cooperative
agreement. To be eligible, they must have uniquely relevant expertise
and skills that will contribute to the training, research, or
administration at the foreign institution and have a major career
commitment to international research. |
| Citizenship or Residency: |
Unrestricted
|
| Activity Location: |
Unrestricted
|
| Requirements: |
Ph.D./M.D./Other Professional Nonprofit Academic Institution
|
| Abstract: |
This FOA, issued by the Fogarty International
Center (FIC), National Institute of Mental Health (NIMH), Office of
Research on Women's Health (ORWH), and National institute on Drug Abuse
(NIDA), solicits renewal (re-competing) and new Phase II applications
in the International Clinical, Operations and Health Services Research
Training Award for AIDS and TB (ICOHRTA AIDS TB) program. The
applications from a Research Training Unit, composed of a Phase I
ICOHRTA AIDS TB (planning grant) recipient and the U.S. partner
institution chosen by the Phase I recipient, must propose, in an
integrated manner, a comprehensive training program that will
strengthen the capacity in the foreign country to conduct clinical
research and implementation science, including operations and health
services research focused on HIV infection, TB, and, where relevant,
HIV/TB co-infection prevention, care and treatment.
The objectives of the ICOHRTA AIDS TB program are to -
develop research training programs for integrated clinical research and
implementation science at foreign institutions in low or middle-income
countries (LMICs) where HIV and/or TB are significant problems (Over
time, these institutions will become national, regional and
international centers of excellence in implementation science for HIV
and /or TB.); - develop a cadre of "implementation science"
experts that can address issues of importance for HIV and TB
prevention, care and treatment in their country and region; -
support training-related research (degree-related or mentored research
projects) that address issues of importance to implementation of HIV
and/or TB interventions and are directly relevant to the needs of the
people in the foreign country, are appropriate to local circumstances
and most likely to affect public health policy; - rapidly strengthen
the research training capacity and infrastructure required for success
by building on existing programs involved with the implementation of
prevention, care and treatment interventions for HIV and/or TB in the
country; and - strengthen core research support capabilities needed to manage research grants at the foreign institution.
Each
Phase II Comprehensive ICOHRTA-AIDS/TB program application should
incorporate an appropriate mix of long-, intermediate- and short-term
training opportunities in a wide range of relevant disciplines and
skills necessary to advance implementation science. The proposed
training should strengthen sustainable clinical research and
implementation science, including operations and health services
research, and core research support capacity at the foreign site.
Training can take place at the U.S. or foreign sites, but
training-related research should be carried out mainly in the country
of the foreign institution. While a range of short-, intermediate- and
long-term training is allowable, emphasis will be on intermediate- to
longer-term training, including mid-career training and advanced
in-country research. |
| Contact Name: |
Ms. Elizabeth Cleveland, Grants Management Officer |
| Contact Address: |
Fogarty International Center National Institutes of Health Building 31, Room B2C29 |
| Contact City: |
Bethesda |
| Contact State: |
Maryland |
| Contact Zip: |
20892-2220 |
| Contact Country: |
United States |
| Contact Phone: |
     +1 (301) 451-6830 |
| Contact Fax: |
+1 (301) 594-1211 |
| Contact Email: |
clevelande@mail.nih.gov |
| URL for more information: |
http://grants1.nih.gov/grants/guide/pa-files/PAR-08-155.html |
| Date Last Revised: |
April 22, 2008 |
| URL from COS to Bookmark this record: |
http://fundingopps.cos.com/cgi-bin/getRec?id=113584 |
| Keywords: |
Health or Nutrition Programs - Developing Countries
HIV
Infectious Diseases or Agents
Tuberculosis
|
| Sponsor Reference No: |
PAR-08-155 |
| Funding Type: |
Collaboration or Cooperative Agreement
Program or Curriculum Development or Provision
|
| COS Unique Id: |
113587 |
| Title: |
Biomarkers of Infection-Associated Cancers (R01) |
| Sponsor: |
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
|
| Sponsor Type: |
Federal, U.S. |
| Deadline: |
June 5, 2008 October 5, 2008 February 5, 2009
|
| Deadline Note: |
The opening date is May 5, 2008. This opportunity will expire on May 8, 2011. |
| Amount Note: |
This FOA uses the NIH research project R01 grant
mechanism. The total project period for an application submitted in
response to this funding opportunity may not exceed five years.
Applicants for an R01 award are not limited in dollars but need to
reflect the actual needs of the proposed project.
This program does not require cost sharing. |
| Eligibility: |
Eligible applicants include institutions of higher
education; nonprofits, for-profits, and small businesses; state and
local governments; eligible agencies of the federal government; and
non-domestic organizations. |
| Citizenship or Residency: |
Unrestricted
|
| Activity Location: |
Unrestricted
|
| Requirements: |
Small Business Ph.D./M.D./Other Professional Commercial Government Nonprofit Academic Institution
|
| Abstract: |
This FOA, issued by the National Cancer Institute
(NCI) and the National Institute of Dental and Craniofacial Research
(NIDCR), encourages applications from institutions and organizations
that propose to identify biomarkers for cancers where the etiology of
the disease is attributed to infectious agents.
This initiative
encourages research to identify molecular markers for risk assessment
and early detection in individuals exposed to infectious agents that
have been linked to cancer. Listed below, but not limited to, are
several programmatic areas in need of support for developing molecular
signatures for infectious agent-associated cancers: 1. Molecular
profiles of normal, precancerous, and cancerous lesions following
infection and of body fluids from infected individuals: Infectious
agents interact with host cells and activate sets of infectious
agent-specific and host-specific genes and proteins. Often some of
these proteins are secreted into extracellular fluids. Samples utilized
for studies may be derived from tissues or body fluids (e.g., serum,
nipple aspirate, pancreatic juice, sputum, urine, alveolar lavage,
saliva). It is advantageous if marker profiles can be obtained from
body fluids that are collected using minimally invasive methodologies.
In addition, chronic inflammation in response to the infectious agent
may play a role in cancer development. It may be possible that
indicators of inflammation or immune activation could also be useful
indices of cancer predisposition.
2. Evaluation of these
molecular profiles for use in gaining a better understanding of the
role of infectious agents in cancer development and use in early
detection, risk assessment, and prevention of cancer: In all known
cases, infectious agents that are associated with cancers persist for
long periods in the host before cancer develops. How the host responds
to the infectious agents and how the agent modulates this response are
critical in allowing for its persistence and may determine the risk of
cancer. Molecular profiles should be analyzed to determine whether a
single biomarker, panel of biomarkers, or molecular patterns can be
used to determine which infected individuals are at risk of developing
cancer and to determine the transition from chronic infection to the
initiation of cancer. These molecular profiles may also be used to
identify targets for cancer prevention and therapeutic vaccine
development.
Research projects proposed in the applications may
involve a number of infectious agents showing associations with cancer.
Noteworthy viral agents of interest to this program are human
papillomavirus (HPV), Hepatitis B and C viruses, Epstein-Barr virus
(EBV), and Simian Virus 40. Furthermore, an escalating prevalence of
early cervical, lung, and colon cancers has emerged among HIV patients.
Applicants are also invited to investigate bacterial etiology in
cancer, such as the role of Helicobacter pylori in the development of
gastric cancers. The involvement of parasitic infections in various
cancers is also relevant to this FOA. The NIDCR has particular interest
in EBV- and HPV-associated head and neck cancers. Research projects
covering basic science (infectious life cycle, viral replication, etc.)
or treatment studies of these infectious agents without direct
relevance to cancer biomarker development are not encouraged by this
FOA.
Using the NIH Research Project Grant (R01) funding
mechanism, this FOA focuses on discrete, specified, circumscribed
projects based upon strong preliminary data. |
| Contact Name: |
Jane Paull |
| Contact Address: |
Office of Grants Administration National Cancer Institute 6120 Executive Boulevard, EPS Room 243, MSC 7150 |
| Contact City: |
Bethesda |
| Contact State: |
Maryland |
| Contact Zip: |
20892-7150 |
| Contact Country: |
United States |
| Contact Phone: |
     +1 (301) 496-2182 |
| Contact Fax: |
+1 (301) 496-8601 |
| Contact Email: |
paullj@mail.nih.gov |
| URL for more information: |
http://grants1.nih.gov/grants/guide/pa-files/PA-08-156.html |
| Date Last Revised: |
April 22, 2008 |
| URL from COS to Bookmark this record: |
http://fundingopps.cos.com/cgi-bin/getRec?id=113587 |
| Keywords: |
Biomarkers
Cancer Biology
|
| Sponsor Reference No: |
PA-08-156 |
| Funding Type: |
Research
|
| COS Unique Id: |
113588 |
| Title: |
Biomarkers of Infection-Associated Cancers (R21) |
| Sponsor: |
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
|
| Sponsor Type: |
Federal, U.S. |
| Deadline: |
June 16, 2008 October 16, 2008 February 16, 2009
|
| Deadline Note: |
The opening date is May 16, 2008. This opportunity will expire on May 8, 2011. |
| Upper Amount: |
$275,000 |
| Amount Note: |
This FOA utilizes the NIH Exploratory/Developmental
Grant (R21) mechanism. The total project period for an application
submitted in response to this funding opportunity may not exceed two
years. Direct costs are limited to $275,000 over an R21 two-year
period, with no more than $200,000 in direct costs allowed in any
single year. The R21 is not renewable.
This program does not require cost sharing. |
| Eligibility: |
Eligible applicants include institutions of higher
education; nonprofits, for-profits, and small businesses; state and
local governments; eligible agencies of the federal government; and
non-domestic organizations. |
| Citizenship or Residency: |
Unrestricted
|
| Activity Location: |
Unrestricted
|
| Requirements: |
Small Business Ph.D./M.D./Other Professional Commercial Government Nonprofit Academic Institution
|
| Abstract: |
This FOA, issued by the National Cancer Institute
(NCI) and the National Institute of Dental and Craniofacial Research
(NIDCR), encourages applications from institutions and organizations
that propose to identify biomarkers for cancers where the etiology of
the disease is attributed to infectious agents.
This initiative
encourages research to identify molecular markers for risk assessment
and early detection in individuals exposed to infectious agents that
have been linked to cancer. Listed below, but not limited to, are
several programmatic areas in need of support for developing molecular
signatures for infectious agent-associated cancers: 1. Molecular
profiles of normal, precancerous, and cancerous lesions following
infection and of body fluids from infected individuals: Infectious
agents interact with host cells and activate sets of infectious
agent-specific and host-specific genes and proteins. Often some of
these proteins are secreted into extracellular fluids. Samples utilized
for studies may be derived from tissues or body fluids (e.g., serum,
nipple aspirate, pancreatic juice, sputum, urine, alveolar lavage,
saliva). It is advantageous if marker profiles can be obtained from
body fluids that are collected using minimally invasive methodologies.
In addition, chronic inflammation in response to the infectious agent
may play a role in cancer development. It may be possible that
indicators of inflammation or immune activation could also be useful
indices of cancer predisposition.
2. Evaluation of these
molecular profiles for use in gaining a better understanding of the
role of infectious agents in cancer development and use in early
detection, risk assessment, and prevention of cancer: In all known
cases, infectious agents that are associated with cancers persist for
long periods in the host before cancer develops. How the host responds
to the infectious agents and how the agent modulates this response are
critical in allowing for its persistence and may determine the risk of
cancer. Molecular profiles should be analyzed to determine whether a
single biomarker, panel of biomarkers, or molecular patterns can be
used to determine which infected individuals are at risk of developing
cancer and to determine the transition from chronic infection to the
initiation of cancer. These molecular profiles may also be used to
identify targets for cancer prevention and therapeutic vaccine
development.
Research projects proposed in the applications may
involve a number of infectious agents showing associations with cancer.
Noteworthy viral agents of interest to this program are human
papillomavirus (HPV), Hepatitis B and C viruses, Epstein-Barr virus
(EBV), and Simian Virus 40. Furthermore, an escalating prevalence of
early cervical, lung, and colon cancers has emerged among HIV patients.
Applicants are also invited to investigate bacterial etiology in
cancer, such as the role of Helicobacter pylori in the development of
gastric cancers. The involvement of parasitic infections in various
cancers is also relevant to this FOA. The NIDCR has particular interest
in EBV- and HPV-associated head and neck cancers. Research projects
covering basic science (infectious life cycle, viral replication, etc.)
or treatment studies of these infectious agents without direct
relevance to cancer biomarker development are not encouraged by this
FOA.
Using the NIH Exploratory Grant (R21) funding mechanism, this FOA focuses on early and conceptual stages of research projects. |
| Contact Name: |
Jane Paull |
| Contact Address: |
Office of Grants Administration National Cancer Institute 6120 Executive Boulevard, EPS Room 243, MSC 7150 |
| Contact City: |
Bethesda |
| Contact State: |
Maryland |
| Contact Zip: |
20892-7150 |
| Contact Country: |
United States |
| Contact Phone: |
     +1 (301) 496-2182 |
| Contact Fax: |
+1 (301) 496-8601 |
| Contact Email: |
paullj@mail.nih.gov |
| URL for more information: |
http://grants1.nih.gov/grants/guide/pa-files/PA-08-157.html |
| Date Last Revised: |
April 22, 2008 |
| URL from COS to Bookmark this record: |
http://fundingopps.cos.com/cgi-bin/getRec?id=113588 |
| Keywords: |
Biomarkers
Cancer Biology
|
| Sponsor Reference No: |
PA-08-157 |
| Funding Type: |
Research
|
| COS Unique Id: |
3063 |
| Title: |
Potts Memorial Foundation Grant |
| Sponsor: |
Potts Memorial Foundation
|
| Sponsor Type: |
Private Foundation |
| Deadline Note: |
Continuous. The trustees of the foundation meet the
first Friday in May and the third Friday in October to consider grants.
Proposals should reach the office at least 30 days prior to each
meeting date. |
| Eligibility: |
Charitable organizations are eligible to apply. |
| Citizenship or Residency: |
Unrestricted
|
| Activity Location: |
Unrestricted
|
| Requirements: |
Nonprofit
|
| Abstract: |
The foundation provides funds for the care,
treatment, and rehabilitation of persons afflicted with tuberculosis.
Support may include maintenance operations of hospitals; research;
vocational counseling and guidance; grants to hospitals and charitable
institutions; and the operation of sheltered workshops. |
| Contact Name: |
Charles E. Inman, Secretary |
| Contact Address: |
Potts Memorial Foundation P.O. Box 1015 |
| Contact City: |
Hudson |
| Contact State: |
New York |
| Contact Zip: |
12534 |
| Contact Country: |
United States |
| Contact Phone: |
     +1 (518) 828-3365 |
| Date Last Revised: |
April 21, 2008 |
| URL from COS to Bookmark this record: |
http://fundingopps.cos.com/cgi-bin/getRec?id=3063 |
| Keywords: |
Patient Care and Education
Rehabilitation or Therapy
Tuberculosis
|
| Funding Type: |
Research
Facility Construction or Operation
Program or Curriculum Development or Provision
|
| COS Unique Id: |
32505 |
| Title: |
Conservation and the Environment |
| Sponsor: |
Mellon Foundation, Andrew W.
|
| Sponsor Type: |
Private Foundation |
| Deadline Note: |
Continuous. Unsolicited proposals are rarely
funded. Prospective applicants are therefore encouraged not to submit a
full proposal initially, but a short query letter that sets forth the
need, nature, and amount of their request, along with evidence of
suitable classification by the Internal Revenue Service. |
| Amount Note: |
Junior Faculty Research Grants have ranged up to approximately $300,000. |
| Citizenship or Residency: |
Unrestricted
|
| Activity Location: |
Unrestricted
|
| Requirements: |
Ph.D./M.D./Other Professional Nonprofit
|
| Abstract: |
The Foundation's program in Conservation and the
Environment (C&E) has evolved from interests originally stated by
the Avalon and Old Dominion Foundations as including the preservation
of natural areas and the support of "organizations concerned with
increasing man's understanding of his natural environment, his relation
to it, and the effects of his activities upon it."
The activities described below are the only areas within which the Foundation is currently accepting inquiries: 1.
Junior Faculty Research grants are awarded to new faculty as they begin
their first tenure-track positions. The awards do not replace start-up
research funds provided by colleges or universities and are only made
after those arrangements are in place. The idea is to provide
intellectual venture capital to promising researchers at the critical
and formative stage when they begin their independent research careers.
This program is devoted to basic research on how natural ecosystems
work. It emphasizes support of leading institutions, innovative
research, and the training of promising doctoral and postdoctoral
researchers. The Foundation limits its activities to the United States
and joint projects with institutions in South Africa that are linked to
its other activities there. 2. The C&E portion of the AWMF South
Africa program is centered on creating research bridges between the
U.S. universities and South African universities, the South African
National Parks System and the South African National Biodiversity
Institution. The Foundation has worked to strengthen the capacity of
these two institutions to work effectively with university scientists
and students - and provided support to engage university research
groups from both South Africa and the USA in collaborative research
with them. The general aims and guidelines for this portion of the
program are the same as those described for Junior Faculty research
grants above. New grants are restricted to proposals that link directly
to the extant program. 3. The African and Latin American Plants
Initiatives are partnerships of 85 herbaria from 31 countries working
to create a database of high quality images of plant type specimens of
African and Latin American plants. The grants are limited to
institutions holding African and Latin American plant type specimens.
The resulting database is available to scholars at www.aluka.org and through www.JSTOR.org.
The Foundation will be glad to hear from any institutions holding
African and/or Latin American plant type specimens that it has not yet
reached. |
| Contact Name: |
William Robertson IV, Program Officer |
| Contact Address: |
Andrew W. Mellon Foundation 140 East 62nd Street |
| Contact City: |
New York |
| Contact State: |
New York |
| Contact Zip: |
10065 |
| Contact Country: |
United States |
| Contact Phone: |
     +1 (212) 500-2497 |
| Contact Fax: |
+1 (212) 500-2302 |
| Contact Email: |
wr@mellon.org |
| URL for more information: |
http://www.mellon.org/grant_programs/programs/conservation |
| Date Last Revised: |
April 25, 2008 |
| URL from COS to Bookmark this record: |
http://fundingopps.cos.com/cgi-bin/getRec?id=32505 |
| Keywords: |
Botany
Ecosystems
Environmental Conservation
Environmental Law
Environmental Sciences
Land Management or Land Use
Terrestrial Ecology
|
| Funding Type: |
Research
Program or Curriculum Development or Provision
|
|
|
©2008, ProQuest LLC All rights reserved
|
|