There are no cures for neurodegenerative protein conformational diseases (PCDs), such as Alzheimer’s disease (AD), Parkinson’s disease (PD), and Huntington’s disease (HD). Emerging evidence suggests the gut microbiota plays a role in their pathogenesis, though the influences of specific bacteria on disease-associated proteins remain elusive.
Test-negative designs are increasingly used to evaluate vaccine effectiveness because of desirable properties like reduced confounding due to healthcare-seeking behaviors and lower cost compared to other study designs. An individual’s decision to seek care often depends on their disease severity, with severe disease more likely to be captured than mild disease.
Melioidosis, a severe bacterial illness caused by Burkholderia pseudomallei, is prevalent in most parts of Thailand, including its southern region situated within the Malay Peninsula. Despite a lower reported incidence rate of melioidosis in the South compared to the Northeast, the mortality rate remains persistently high.
The UF Emerging Pathogens Institute has assembled a multidisciplinary working group to research a swiftly spreading bird flu strain and help prepare Florida’s response to potential outbreaks.
Daniel Swale works at the intersection of physiology and toxicology. Combining these two to create physiotoxicology, Swale's research both develops insecticides and enhances honeybees' immune systems.
Neglected tropical diseases (NTDs), particularly those caused by trypanosomatid protozoa, impose a significant global burden, disproportionately affecting underserved communities in tropical and subtropical regions. Despite their high mortality rates, associated chronic conditions, and rapid spread due to globalization and climate change, NTDs have historically received minimal research investment.
Typhoid fever caused by Salmonella enterica serovar Typhi (S. typhi) continues to pose a significant risk to public health in developing countries, including Pakistan. This study investigated the epidemiological factors linked to suspected and confirmed S. typhi infections in Peshawar’s hospital population.
Vancomycin-resistant enterococci (VRE) are a major cause of healthcare-associated infections, with an estimated 54,500 cases among hospitalized patients and 5400 deaths per year associated with VRE in the United States alone. In particular, patients with underlying hematologic malignancies such as leukemia and patients undergoing hematopoietic cell transplant (HCT) and solid organ transplant are at higher risk for VRE acquisition and infections due to their weakened immune system and multiple courses of antibiotics.
Olympic triathletes dove into the Seine River on Wednesday after organizers declared the water in Paris safe for swimming following days of concerns about elevated bacteria levels caused by heavy rains last week.
Pathogens can be collected from air and detected in samples by many methods. However, merely detecting pathogens does not answer whether they can spread disease. To fully assess health risks from exposure to airborne pathogens, the infectivity of those agents must be assessed.
