Chemotherapy is a primary treatment for cancer, but its efficacy is often limited by cancer-associated bacteria (CAB) that impair tumor suppressor functions. Our previous research found that Mycoplasma fermentans DnaK, a chaperone protein, impairs p53 activities, which are essential for most anti-cancer chemotherapeutic responses.
Global collaborations remain a recurring theme at EPI Research Day 2024, emphasizing their impact in driving breakthroughs in infectious diseases.
University of Florida College of Veterinary Medicine assistant scientist Jeff Gruntmeir, Ph.D., won first place in the early-stage investigator poster competition at EPI Research Day 2024.
Sebastian Botero-Cañola, a postdoctoral associate at the UF College of Agricultural and Life Sciences, won first place in the post-doctoral poster competition at EPI Research Day 2024.
University of Florida College of Agricultural and Life Sciences Ph.D. candidate Tingting Gu explored the implications of Listeria’s symbiosis with other background microflora on food contact surfaces.
Concentrations of tenofovir diphosphate (TFV-DP) and lamivudine triphosphate (3TC-TP) in cells are correlates of medication adherence and antiviral activity. However, studies have yet to characterize the simultaneous relationship between TFV-DP and 3TC-TP concentrations with HIV and hepatitis B virus (HBV) suppression.
In addition to preying on endangered native wildlife, the invasive Burmese python also brought a deadly parasite to Florida’s snakes: Raillietiella orientalis, also known as snake lungworm.
The impact of extracorporeal membrane oxygenation (ECMO) on the pharmacokinetics/dynamics (PK/PD) of beta-lactam antibiotics have not been well studied in general, but cefepime specifically has the least amount of data. We aimed to investigate whether ECMO alters the PK of cefepime in adult intensive care unit (ICU) patients.
The field of global health aims to leverage global partnerships to investigate issues transcending local boundaries. It acknowledges the importance of forming collaborative teams with diverse knowledge and experience to combat health disparities.
The differentiation of dengue virus (DENV) infection, a major cause of acute febrile illness in tropical regions, from other etiologies, may help prioritize laboratory testing and limit the inappropriate use of antibiotics. While traditional clinical prediction models focus on individual patient-level parameters, we hypothesize that for infectious diseases, population-level data sources may improve predictive ability.
