Jeffrey R Bloomquist,
PROF
Department:
AG-ENTOMOLOGY AND NEMATOLOGY
Business Phone:
(352) 273-9417
Business Email:
jbquist@ufl.edu
Teaching Profile
Courses Taught
2010,2014-2016,2016-2021,2021
ENY6934 Selected Studies in Entomology
2011-2013,2015-2021,2020-2021
ENY6651C Insect Toxicology
2011-2012,2019-2020
ENY6905 Problems in Entomology
Research Profile
Open Researcher and Contributor ID (ORCID)
0000-0002-9136-4998
Publications
2023
Differences in excito‐repellent behavior between susceptible and permethrin‐resistant strains of Aedes aegypti upon exposure to insecticide‐treated fabric
Pest Management Science.
[DOI] 10.1002/ps.7785.
2023
Neurophysiological action of centrally-acting spider toxin polypeptides derived from Hadronyche versuta and Tegenaria agrestis venoms.
Pesticide biochemistry and physiology.
192
[DOI] 10.1016/j.pestbp.2023.105416.
[PMID] 37105624.
2023
Structural Exploration of Novel Pyrethroid Esters and Amides for Repellent and Insecticidal Activity against Mosquitoes
Journal of Agricultural and Food Chemistry.
71(47):18285-18291
[DOI] 10.1021/acs.jafc.3c01839.
2022
Honey Bee (Apis mellifera) Exposure to Pesticide Residues in Nectar and Pollen in Urban and Suburban Environments from Four Regions of the United States.
Environmental toxicology and chemistry.
41(4):991-1003
[DOI] 10.1002/etc.5298.
[PMID] 35262221.
2022
Mode of action and toxicological effects of the sesquiterpenoid, nootkatone, in insects.
Pesticide biochemistry and physiology.
183
[DOI] 10.1016/j.pestbp.2022.105085.
[PMID] 35430075.
2022
Nutritional status significantly affects toxicological endpoints in the CDC bottle bioassay
Pest Management Science.
78(2):743-748
[DOI] 10.1002/ps.6687.
2022
Sodium channel-directed alkaloids synergize the mosquitocidal and neurophysiological effects of natural pyrethrins.
Pesticide biochemistry and physiology.
186
[DOI] 10.1016/j.pestbp.2022.105171.
[PMID] 35973763.
2022
Studies on the Volatiles Composition of Stored Sheep Wool, and Attractancy toward Aedes aegypti Mosquitoes
Insects.
13(2)
[DOI] 10.3390/insects13020208.
[PMID] 35206782.
2022
Testing new compounds for efficacy against Varroa destructor and safety to honey bees (Apis mellifera).
Pest management science.
78(1):159-165
[DOI] 10.1002/ps.6617.
[PMID] 34464499.
2021
A Survey of Chemoreceptive Responses on Different Mosquito Appendages.
Journal of medical entomology.
58(1):475-479
[DOI] 10.1093/jme/tjaa154.
[PMID] 32740665.
2021
Bioactivities and modes of action of VUAA1
Pest Management Science.
77(8):3685-3692
[DOI] 10.1002/ps.6023.
2021
Chemical Treatments for Insect Cell Differentiation: The Effects of 20-Hydroxyecdysone and Veratridine on Cultured Spodoptera frugiperda (Sf21) Insect Cell Ultrastructure
Insects.
13(1)
[DOI] 10.3390/insects13010032.
[PMID] 35055875.
2021
Co-Toxicity Factor Analysis Reveals Numerous Plant Essential Oils Are Synergists of Natural Pyrethrins against Aedes aegypti Mosquitoes
Insects.
12(2)
[DOI] 10.3390/insects12020154.
[PMID] 33670293.
2021
Development of an a priori computational approach for brain uptake of compounds in an insect model system.
Bioorganic & medicinal chemistry letters.
40
[DOI] 10.1016/j.bmcl.2021.127930.
[PMID] 33711441.
2021
Enhanced pyrethroid potency in Drosophila melanogaster expressing voltage-gated potassium channel mutants: Insecticidal activity and neuronal action.
Pesticide biochemistry and physiology.
178
[DOI] 10.1016/j.pestbp.2021.104940.
[PMID] 34446207.
2021
Heterocyclic Amine-Induced Feeding Deterrence and Antennal Response of Honey Bees
Insects.
12(1)
[DOI] 10.3390/insects12010069.
[PMID] 33466620.
2021
Overexposing mosquitoes to insecticides under global warming: A public health concern?
The Science of the total environment.
762
[DOI] 10.1016/j.scitotenv.2020.143069.
[PMID] 33127158.
2021
Recording central neurophysiological output from mosquito larvae for neuropharmacological and insecticide resistance studies.
Journal of insect physiology.
135
[DOI] 10.1016/j.jinsphys.2021.104319.
[PMID] 34627851.
2021
Resistance-Breaking Insecticidal Activity of New Spatial Insecticides against Aedes aegypti.
Journal of agricultural and food chemistry.
69(33):9684-9692
[DOI] 10.1021/acs.jafc.1c01200.
[PMID] 34387470.
2021
Synergistic effects of potassium channel blockers and pyrethroids: mosquitocidal activity and neuronal mode of action†
Pest Management Science.
77(8):3673-3684
[DOI] 10.1002/ps.6112.
2021
Toxicity and mode of action of the aporphine plant alkaloid liriodenine on the insect GABA receptor
Toxicon.
201:141-147
[DOI] 10.1016/j.toxicon.2021.08.019.
2021
Vapor phase repellency and insecticidal activity of pyridinyl amides against anopheline mosquitoes
Current Research in Parasitology & Vector-Borne Diseases.
1
[DOI] 10.1016/j.crpvbd.2021.100062.
[PMID] 35284890.
2020
Mosquitocidal activity of p,p’-difluoro-diphenyl-trichloroethane (DFDT).
Pesticide biochemistry and physiology.
170
[DOI] 10.1016/j.pestbp.2020.104686.
[PMID] 32980070.
2020
Pyrethroid-Derived Acids and Alcohols: Bioactivity and Synergistic Effects on Mosquito Repellency and Toxicity.
Journal of agricultural and food chemistry.
68(10):3061-3070
[DOI] 10.1021/acs.jafc.9b07979.
[PMID] 32059103.
2020
Reduced effectiveness of repellents in a pyrethroid‐resistant strain of Aedes aegypti (Diptera: culicidae) and its correlation with olfactory sensitivity
Pest Management Science.
76(1):118-124
[DOI] 10.1002/ps.5562.
2020
Screening for Enhancement of Permethrin Toxicity by Plant Essential Oils Against Adult Females of the Yellow Fever Mosquito (Diptera: Culicidae).
Journal of medical entomology.
57(4):1149-1156
[DOI] 10.1093/jme/tjaa014.
[PMID] 32020196.
2020
Structure-Activity Relationship Analysis of Potential New Vapor-Active Insect Repellents.
Journal of agricultural and food chemistry.
68(47):13960-13969
[DOI] 10.1021/acs.jafc.0c03333.
[PMID] 33147044.
2020
Terpenoid-Induced Feeding Deterrence and Antennal Response of Honey Bees
Insects.
11(2)
[DOI] 10.3390/insects11020083.
[PMID] 31979399.
2020
Voltage-gated chloride channel blocker DIDS as an acaricide for Varroa mites.
Pesticide biochemistry and physiology.
167
[DOI] 10.1016/j.pestbp.2020.104603.
[PMID] 32527437.
2019
Chronic toxicity of clothianidin, imidacloprid, chlorpyrifos, and dimethoate to Apis mellifera L. larvae reared in vitro.
Pest management science.
75(1):29-36
[DOI] 10.1002/ps.5124.
[PMID] 29931787.
2019
Gone in 60 seconds: Sub-lethal Effects of Metofluthrin Vapors on Behavior and Fitness of Resistant and Field Strains of Aedes aegypti (Diptera: Culicidae).
Journal of medical entomology.
56(4):1087-1094
[DOI] 10.1093/jme/tjz048.
[PMID] 30989189.
2019
High-throughput screening method for evaluating spatial repellency and vapour toxicity to mosquitoes.
Medical and veterinary entomology.
33(3):388-396
[DOI] 10.1111/mve.12377.
[PMID] 30907445.
2019
Insecticidal and repellent properties of novel trifluoromethylphenyl amides III.
Pesticide biochemistry and physiology.
161:5-11
[DOI] 10.1016/j.pestbp.2019.06.012.
[PMID] 31685196.
2019
Is DEET a dangerous neurotoxicant?
Pest Management Science.
75(8):2068-2070
[DOI] 10.1002/ps.5476.
2019
Mosquito Acetylcholinesterase as a Target for Novel Phenyl-Substituted Carbamates
International Journal of Environmental Research and Public Health.
16(9)
[DOI] 10.3390/ijerph16091500.
[PMID] 31035318.
2018
Characterizing Permethrin and Etofenprox Resistance in Two Common Laboratory Strains of Anopheles gambiae (Diptera: Culicidae).
Insects.
9(4)
[DOI] 10.3390/insects9040146.
[PMID] 30360362.
2018
Electrophysiological Recording of The Central Nervous System Activity of Third-Instar Drosophila Melanogaster.
Journal of visualized experiments : JoVE.
(141)
[DOI] 10.3791/58375.
[PMID] 30531714.
2018
Fatty Acid and Related Potassium Kv2 Channel Blockers: Toxicity and Physiological Actions on Mosquitoes
Insects.
9(4)
[DOI] 10.3390/insects9040155.
[PMID] 30388752.
2018
Insecticidal and repellent properties of novel trifluoromethylphenyl amides II.
Pesticide biochemistry and physiology.
151:40-46
[DOI] 10.1016/j.pestbp.2018.08.006.
[PMID] 30704711.
2018
Pharmacology of central octopaminergic and muscarinic pathways in Drosophila melanogaster larvae: Assessing the target potential of GPCRs.
Pesticide biochemistry and physiology.
151:53-58
[DOI] 10.1016/j.pestbp.2018.08.001.
[PMID] 30704713.
2018
Select β- and γ-branched 1-alkylpyrazol-4-yl methylcarbamates exhibit high selectivity for inhibition of Anopheles gambiae versus human acetylcholinesterase.
Pesticide biochemistry and physiology.
151:32-39
[DOI] 10.1016/j.pestbp.2018.02.003.
[PMID] 30524149.
2018
Synthesis and structure-activity relationships of carbohydrazides and 1,3,4-oxadiazole derivatives bearing an imidazolidine moiety against the yellow fever and dengue vector, Aedes aegypti.
Pest management science.
74(2):413-421
[DOI] 10.1002/ps.4722.
[PMID] 28869331.
2018
The impacts of chlorothalonil and diflubenzuron on Apis mellifera L. larvae reared in vitro.
Ecotoxicology and environmental safety.
164:283-288
[DOI] 10.1016/j.ecoenv.2018.08.039.
[PMID] 30125774.
2018
Toxicity, mode of action, and synergist potential of flonicamid against mosquitoes.
Pesticide biochemistry and physiology.
151:3-9
[DOI] 10.1016/j.pestbp.2018.06.004.
[PMID] 30704710.
2018
Vapor toxicity of five volatile pyrethroids against Aedes aegypti, Aedes albopictus, Culex quinquefasciatus, and Anopheles quadrimaculatus (Diptera: Culicidae).
Pest management science.
74(12):2699-2706
[DOI] 10.1002/ps.5088.
[PMID] 29797795.
2017
Amitraz and its metabolite modulate honey bee cardiac function and tolerance to viral infection.
Journal of invertebrate pathology.
149:119-126
[DOI] 10.1016/j.jip.2017.08.005.
[PMID] 28797906.
2017
Application Site and Mosquito Age Influences Malathion- and Permethrin-Induced Mortality in Culex quinquefasciatus (Diptera: Culicidae).
Journal of medical entomology.
54(6):1692-1698
[DOI] 10.1093/jme/tjx160.
[PMID] 28968685.
2017
ATP-sensitive inwardly rectifying potassium channel modulators alter cardiac function in honey bees.
Journal of insect physiology.
99:95-100
[DOI] 10.1016/j.jinsphys.2017.04.005.
[PMID] 28412203.
2017
Determination of metabolic resistance mechanisms in pyrethroid-resistant and fipronil-tolerant brown dog ticks.
Medical and veterinary entomology.
31(3):243-251
[DOI] 10.1111/mve.12240.
[PMID] 28639697.
2017
Discovery of Species-selective and Resistance-breaking Anticholinesterase Insecticides for the Malaria Mosquito.
Current medicinal chemistry.
24(27):2946-2958
[DOI] 10.2174/0929867324666170206130024.
[PMID] 28176636.
2017
Mosquitocidal Activity and Mode of Action of the Isoxazoline Fluralaner.
International journal of environmental research and public health.
14(2)
[DOI] 10.3390/ijerph14020154.
[PMID] 28178191.
2017
N’-mono- and N, N’-diacyl derivatives of benzyl and arylhydrazines as contact insecticides against adult Anopheles gambiae.
Pesticide biochemistry and physiology.
143:33-38
[DOI] 10.1016/j.pestbp.2017.10.001.
[PMID] 29183608.
2017
Permethrin and malathion LD90 values for Culex quinquefasciatus vary with topical application site.
Medical and veterinary entomology.
31(3):306-311
[DOI] 10.1111/mve.12236.
[PMID] 28421653.
2017
Pyrethroid resistance alters the blood-feeding behavior in Puerto Rican Aedes aegypti mosquitoes exposed to treated fabric.
PLoS neglected tropical diseases.
11(9)
[DOI] 10.1371/journal.pntd.0005954.
[PMID] 28931018.
2017
Sarniensine, a mesembrine-type alkaloid isolated from Nerine sarniensis, an indigenous South African Amaryllidaceae, with larvicidal and adulticidal activities against Aedes aegypti.
Fitoterapia.
116:34-38
[DOI] 10.1016/j.fitote.2016.11.007.
[PMID] 27864138.
2017
Toxicity and Synergistic Activities of Chalcones Against Aedes aegypti (Diptera: Culicidae) and Drosophila melanogaster (Diptera: Drosophilidae).
Journal of medical entomology.
54(2):382-386
[DOI] 10.1093/jme/tjw183.
[PMID] 28011724.
2017
Toxicology of potassium channel-directed compounds in mosquitoes.
Neurotoxicology.
60:214-223
[DOI] 10.1016/j.neuro.2016.05.021.
[PMID] 27262624.
2017
Voltage-sensitive potassium channels expressed after 20-Hydroxyecdysone treatment of a mosquito cell line.
Insect biochemistry and molecular biology.
87:75-80
[DOI] 10.1016/j.ibmb.2017.06.012.
[PMID] 28668511.
2016
Alkaloids with Activity against the Zika Virus Vector Aedes aegypti (L.)-Crinsarnine and Sarniensinol, Two New Crinine and Mesembrine Type Alkaloids Isolated from the South African Plant Nerine sarniensis.
Molecules (Basel, Switzerland).
21(11)
[PMID] 27801807.
2016
An insecticide resistance-breaking mosquitocide targeting inward rectifier potassium channels in vectors of Zika virus and malaria.
Scientific reports.
6
[DOI] 10.1038/srep36954.
[PMID] 27849039.
2016
Bivalent Carbamates as Novel Control Agents of the Malaria Mosquito, Anopheles gambiae.
Chimia.
70(10):704-708
[PMID] 27779928.
2016
Impact of Topical Application Site On the Efficacy of Permethrin and Malathion To Culex quinquefasciatus.
Journal of the American Mosquito Control Association.
32(4):300-307
[DOI] 10.2987/16-6584.1.
[PMID] 28206864.
2016
Insecticide sensitivity of native chloride and sodium channels in a mosquito cell line.
Pesticide biochemistry and physiology.
130:59-64
[DOI] 10.1016/j.pestbp.2015.11.012.
[PMID] 27155485.
2016
Lantana montevidensis Essential Oil: Chemical Composition and Mosquito Repellent Activity against Aedes aegypti.
Natural product communications.
11(11):1713-1716
[PMID] 30475514.
2016
Toxicity and Physiological Actions of Carbonic Anhydrase Inhibitors to Aedes aegypti and Drosophila melanogaster.
Insects.
8(1)
[DOI] 10.3390/insects8010002.
[PMID] 28025488.
2015
3-Oxoisoxazole-2(3H)-carboxamides and isoxazol-3-yl carbamates: Resistance-breaking acetylcholinesterase inhibitors targeting the malaria mosquito, Anopheles gambiae.
Bioorganic & medicinal chemistry.
23(6):1321-40
[DOI] 10.1016/j.bmc.2015.01.026.
[PMID] 25684426.
2015
A method for assessing chemically-induced paralysis in headless mosquito larvae.
MethodsX.
2:19-23
[DOI] 10.1016/j.mex.2014.12.002.
[PMID] 26844208.
2015
Acute Toxicity and Sublethal Effects of Fenpyroximate to Amblyseius swirskii (Acari: Phytoseiidae).
Journal of economic entomology.
108(3):1047-53
[DOI] 10.1093/jee/tov033.
[PMID] 26470228.
2015
Carbamate and pyrethroid resistance in the akron strain of Anopheles gambiae.
Pesticide biochemistry and physiology.
121:116-21
[DOI] 10.1016/j.pestbp.2015.03.001.
[PMID] 26047119.
2015
Chemical control of the Asian citrus psyllid and of huanglongbing disease in citrus.
Pest management science.
71(6):808-23
[DOI] 10.1002/ps.3957.
[PMID] 25491482.
2015
Difluoromethyl ketones: Potent inhibitors of wild type and carbamate-insensitive G119S mutant Anopheles gambiae acetylcholinesterase.
Bioorganic & medicinal chemistry letters.
25(20):4405-11
[DOI] 10.1016/j.bmcl.2015.09.019.
[PMID] 26386602.
2015
Mosquitocidal carbamates with low toxicity to agricultural pests: an advantageous property for insecticide resistance management.
Pest management science.
71(8):1158-64
[DOI] 10.1002/ps.3899.
[PMID] 25185896.
2015
Pre-treatment of Stegomyia aegypti mosquitoes with a sublethal dose of imidacloprid impairs behavioural avoidance induced by lemon oil and DEET.
Medical and veterinary entomology.
29(1):99-103
[DOI] 10.1111/mve.12082.
[PMID] 25155403.
2015
ROLE OF SERUM AND ION CHANNEL BLOCK ON GROWTH AND HORMONALLY-INDUCED DIFFERENTIATION OF Spodoptera frugiperda (Sf21) INSECT CELLS.
Archives of insect biochemistry and physiology.
90(3):131-9
[DOI] 10.1002/arch.21249.
[PMID] 26183110.
2014
Acetylcholinesterase of the sand fly, Phlebotomus papatasi (Scopoli): construction, expression and biochemical properties of the G119S orthologous mutant.
Parasites & vectors.
7
[DOI] 10.1186/s13071-014-0577-4.
[PMID] 25491113.
2014
Neurotoxicity and mode of action of N, N-diethyl-meta-toluamide (DEET).
PloS one.
9(8)
[DOI] 10.1371/journal.pone.0103713.
[PMID] 25101788.
2013
Aryl methylcarbamates: potency and selectivity towards wild-type and carbamate-insensitive (G119S) Anopheles gambiae acetylcholinesterase, and toxicity to G3 strain An. gambiae.
Chemico-biological interactions.
203(1):314-8
[DOI] 10.1016/j.cbi.2012.09.001.
[PMID] 22989775.
2013
Consequences of manganese administration for striatal dopamine and motor behavior in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-exposed C57BL/6 mice.
Human & experimental toxicology.
32(8):865-80
[DOI] 10.1177/0960327112469043.
[PMID] 23263854.
2013
Effects of Anticholinesterases on Catalysis and Induced Conformational Change of the Peripheral Anionic Site of Murine Acetylcholinesterase.
Pesticide biochemistry and physiology.
106(3):79-84
[PMID] 24003261.
2013
Inhibitor profile of bis(n)-tacrines and N-methylcarbamates on acetylcholinesterase from Rhipicephalus (Boophilus) microplus and Phlebotomus papatasi.
Pesticide biochemistry and physiology.
106(3)
[DOI] 10.1016/j.pestbp.2013.03.005.
[PMID] 24187393.
2013
Insecticidal, repellent and fungicidal properties of novel trifluoromethylphenyl amides.
Pesticide biochemistry and physiology.
107(1):138-47
[DOI] 10.1016/j.pestbp.2013.06.006.
[PMID] 25149248.
2013
Neurotoxicology of bis(n)-tacrines on Blattella germanica and Drosophila melanogaster acetylcholinesterase.
Archives of insect biochemistry and physiology.
83(4):180-94
[DOI] 10.1002/arch.21104.
[PMID] 23740645.
2013
Plant essential oils affect the toxicities of carbaryl and permethrin against Aedes aegypti (Diptera: Culicidae).
Journal of medical entomology.
50(4):826-32
[PMID] 23926781.
2013
Quinuclidine compounds differently act as agonists of Kenyon cell nicotinic acetylcholine receptors and induced distinct effect on insect ganglionic depolarizations.
Invertebrate neuroscience : IN.
13(2):167-77
[DOI] 10.1007/s10158-013-0160-2.
[PMID] 23884575.
2013
Voltage-sensitive chloride ion channels in Anopheles gambiae Sua-1B cells.
Invertebrate neuroscience : IN.
13(1):57-62
[DOI] 10.1007/s10158-012-0143-8.
[PMID] 23160708.
2012
Induction and inhibition of an apparent neuronal phenotype in Spodoptera frugiperda insect cells (Sf21) by chemical agents.
Invertebrate neuroscience : IN.
12(2):119-27
[DOI] 10.1007/s10158-012-0138-5.
[PMID] 22797937.
2012
Novel models for assessing blood-brain barrier drug permeation.
Expert opinion on drug metabolism & toxicology.
8(6):647-53
[DOI] 10.1517/17425255.2012.677433.
[PMID] 22468700.
2012
Re-engineering aryl methylcarbamates to confer high selectivity for inhibition of Anopheles gambiae versus human acetylcholinesterase.
Bioorganic & medicinal chemistry letters.
22(14):4593-8
[DOI] 10.1016/j.bmcl.2012.05.103.
[PMID] 22738634.
2012
Select small core structure carbamates exhibit high contact toxicity to “carbamate-resistant” strain malaria mosquitoes, Anopheles gambiae (Akron).
PloS one.
7(10)
[DOI] 10.1371/journal.pone.0046712.
[PMID] 23049714.
2010
Monitoring for imidacloprid resistance in the tobacco-adapted form of the green peach aphid, Myzus persicae (Sulzer) (Hemiptera: Aphididae), in the eastern United States.
Pest management science.
66(6):676-85
[DOI] 10.1002/ps.1929.
[PMID] 20309995.
2009
Esterase-based resistance in the tobacco-adapted form of the green peach aphid, Myzus persicae (Sulzer) (Hemiptera: Aphididae) in the eastern United States.
Archives of insect biochemistry and physiology.
72(2):105-23
[DOI] 10.1002/arch.20326.
[PMID] 19557739.
2009
Toxicity and disruption of midgut physiology in larvae of the European corn borer, Ostrinia nubilalis, by anion transporter blockers.
Archives of insect biochemistry and physiology.
70(3):151-61
[DOI] 10.1002/arch.20287.
[PMID] 19140151.
2008
Nematicidal activity of anion transport blockers against Meloidogyne incognita, Caenorhabditis elegans and Heterorhabditis bacteriophora.
Pest management science.
64(6):646-53
[DOI] 10.1002/ps.1591.
[PMID] 18407564.
2008
Towards a species-selective acetylcholinesterase inhibitor to control the mosquito vector of malaria, Anopheles gambiae.
Chemico-biological interactions.
175(1-3):368-75
[DOI] 10.1016/j.cbi.2008.04.037.
[PMID] 18554580.
2007
Neurotoxicity in murine striatal dopaminergic pathways following long-term application of low doses of permethrin and MPTP.
Toxicology letters.
171(3):154-61
[PMID] 17597311.
2007
Structure-activity relationships of pentacycloundecylamines at the N-methyl-d-aspartate receptor.
Bioorganic & medicinal chemistry.
15(3):1525-32
[PMID] 17157509.
2006
Potentiating effect of the ATP-sensitive potassium channel blocker glibenclamide on complex I inhibitor neurotoxicity in vitro and in vivo.
Neurotoxicology.
27(5):826-34
[PMID] 16725203.
2005
Developmental regulation of a turkey intestinal peptide transporter (PepT1).
Poultry science.
84(1):75-82
[PMID] 15685945.
2005
Pharmacology and structure-activity relationships of bioactive polycyclic cage compounds: a focus on pentacycloundecane derivatives.
Medicinal research reviews.
25(1):21-48
[PMID] 15389731.
2004
Synthesis and anticonvulsant evaluation of some new 2-substituted-3-arylpyrido[2,3-d]pyrimidinones.
Bioorganic & medicinal chemistry.
12(21):5711-7
[PMID] 15465347.
2004
Synthesis and biological evaluation of pentacyclo[5.4.0.0(2,6).0(3,10).0(5,9)]undecane derivatives as potential therapeutic agents in Parkinson’s disease.
Bioorganic & medicinal chemistry.
12(7):1799-806
[PMID] 15028270.
2003
Chloride channels as tools for developing selective insecticides.
Archives of insect biochemistry and physiology.
54(4):145-56
[PMID] 14635176.
2003
Differential up-regulation of striatal dopamine transporter and alpha-synuclein by the pyrethroid insecticide permethrin.
Toxicology and applied pharmacology.
192(3):287-93
[PMID] 14575646.
2003
Mode of action of atracotoxin at central and peripheral synapses of insects.
Invertebrate neuroscience : IN.
5(1):45-50
[PMID] 14608494.
2002
Discovery of non-zwitterionic GABA(A) receptor full agonists and a superagonist.
Bioorganic & medicinal chemistry letters.
12(15):1985-8
[PMID] 12113824.
2002
Metabolic studies on haloperidol and its tetrahydropyridinyl dehydration product (HPTP) in C57BL/6 mouse brain preparations.
Neurotoxicity research.
4(1):51-8
[PMID] 12826493.
2002
Molecular cloning and functional expression of a chicken intestinal peptide transporter (cPepT1) in Xenopus oocytes and Chinese hamster ovary cells.
The Journal of nutrition.
132(3):387-93
[PMID] 11880560.
2001
Expression of a cloned ovine gastrointestinal peptide transporter (oPepT1) in Xenopus oocytes induces uptake of oligopeptides in vitro.
The Journal of nutrition.
131(4):1264-70
[PMID] 11285336.
2001
Insecticidal arylalkylbenzhydrolpiperidines: novel inhibitors of voltage-sensitive sodium and calcium channels in mammalian brain.
Pest management science.
57(10):889-95
[PMID] 11695181.
2001
Neurotoxicity of the organochlorine insecticide heptachlor to murine striatal dopaminergic pathways.
Toxicological sciences : an official journal of the Society of Toxicology.
61(1):100-6
[PMID] 11294980.
2001
Pharmacological properties of the MPTP analog trans-1-methyl-4-[4-dimethylaminophenylethenyl]-1,2,3,6-tetrahydropyridine and its pyridinium metabolite in mouse brain synaptosomes: a potential visual marker for substrates of MPTP-induced neurotoxicity.
Progress in neuro-psychopharmacology & biological psychiatry.
25(3):591-608
[PMID] 11370999.
1999
Heptachlor alters expression and function of dopamine transporters.
Neurotoxicology.
20(4):631-7
[PMID] 10499361.
1999
p-Fluorophenylglycine in the urine of baboons treated with HPTP, the tetrahydropyridine analog of haloperidol.
Life sciences.
65(5):535-42
[PMID] 10462080.
1998
Effects of haloperidol metabolites on neurotransmitter uptake and release: possible role in neurotoxicity and tardive dyskinesia.
Brain research.
788(1-2):215-22
[PMID] 9555021.
1998
Novel insecticidal peptides from Tegenaria agrestis spider venom may have a direct effect on the insect central nervous system.
Archives of insect biochemistry and physiology.
38(1):19-31
[PMID] 9589602.
1997
Poly(A)+ RNA from sheep omasal epithelium induces expression of a peptide transport protein(s) in Xenopus laevis oocytes.
Journal of animal science.
75(12):3323-30
[PMID] 9420008.
1997
Potential metabolic bioactivation pathways involving cyclic tertiary amines and azaarenes.
Chemical research in toxicology.
10(9):924-40
[PMID] 9305573.
1996
Demonstration and characterization of dipeptide transport system activity in sheep omasal epithelium by expression of mRNA in Xenopus laevis oocytes.
Journal of animal science.
74(7):1720-7
[PMID] 8818821.
1996
Ion channels as targets for insecticides.
Annual review of entomology.
41:163-90
[PMID] 8546445.
1996
Mode of action of an insecticidal peptide toxin from the venom of a weaving spider (Diguetia canities).
Toxicon : official journal of the International Society on Toxinology.
34(9):1072-5
[PMID] 8896202.
1995
Resistance to avermectins: extent, mechanisms, and management implications.
Annual review of entomology.
40:1-30
[PMID] 7810984.
1994
1-Methyl-4-phenylpyridinium-like neurotoxicity of a pyridinium metabolite derived from haloperidol: cell culture and neurotransmitter uptake studies.
The Journal of pharmacology and experimental therapeutics.
270(2):822-30
[PMID] 8071874.
1994
Cyclodiene resistance at the insect GABA receptor/chloride channel complex confers broad cross resistance to convulsants and experimental phenylpyrazole insecticides.
Archives of insect biochemistry and physiology.
26(1):69-79
[PMID] 8054658.
1993
Toxicology, mode of action and target site-mediated resistance to insecticides acting on chloride channels.
Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology.
106(2):301-14
[PMID] 7904908.
1992
Expression of a gene encoding a scorpion insectotoxin peptide in yeast, bacteria and plants.
Gene.
116(2):165-72
[PMID] 1634114.
1992
Intrinsic lethality of chloride-channel-directed insecticides and convulsants in mammals.
Toxicology letters.
60(3):289-98
[PMID] 1375788.
1992
Reduced neuronal sensitivity to dieldrin and picrotoxinin in a cyclodiene-resistant strain of Drosophila melanogaster (Meigen).
Archives of insect biochemistry and physiology.
19(1):17-25
[PMID] 1311215.
1991
Prolonged exposure to GABA activates GABA-gated chloride channels in the presence of channel-blocking convulsants.
Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology.
99(3):397-402
[PMID] 1685414.
1989
Activation of sodium channels and inhibition of [3H]batrachotoxinin A-20-alpha-benzoate binding by an N-alkylamide neurotoxin.
Molecular pharmacology.
36(2):280-4
[PMID] 2549384.
1989
Neurotoxic actions of pyrethroid insecticides.
Annual review of entomology.
34:77-96
[PMID] 2539040.
1988
Pyrethroid insecticides and DDT modify alkaloid-dependent sodium channel activation and its enhancement by sea anemone toxin.
Molecular pharmacology.
33(5):543-50
[PMID] 2452970.
1987
Differences in the action of avermectin B1a on the GABAA receptor complex of mouse and rat.
Biochemical and biophysical research communications.
146(2):692-8
[PMID] 3039987.
1987
Pharmacological characterization of the voltage-dependent sodium channels of rainbow trout brain synaptosomes.
Brain research.
437(1):77-82
[PMID] 2448013.
1986
Inhibition of gamma-aminobutyric acid-stimulated chloride flux in mouse brain vesicles by polychlorocycloalkane and pyrethroid insecticides.
Neurotoxicology.
7(3):11-20
[PMID] 2434890.
1986
Sodium channel neurotoxins as probes of the knockdown resistance mechanism.
Neurotoxicology.
7(1):217-23
[PMID] 2423935.
1985
Neurotoxic insecticides inhibit GABA-dependent chloride uptake by mouse brain vesicles.
Biochemical and biophysical research communications.
133(1):37-43
[PMID] 3000377.
Grants
May 2023
ACTIVE
Development of resistance-breaking aphicides with a novel mode- and mechanism- of action
Role: Co-Project Director/Principal Investigator
Funding: US DEPT OF AG NATL INST OF FOOD AND AG
Feb 2023
ACTIVE
Insecticide Mode of Action Studies with Pogostone
Role: Principal Investigator
Funding: PYRONE SYSTEMS
Jul 2022
ACTIVE
CDC Southeastern Center of Excellence in Vector-Borne Diseases: Gateway Program
Role: Co-Project Director/Principal Investigator
Funding: CTRS FOR DISEASE CONTROL AND PREVENTION
Mar 2022
– Oct 2022
Insect Activity Screens with Pogostone
Role: Principal Investigator
Funding: PYRONE SYSTEMS
Aug 2021
ACTIVE
Developing resistance-breaking insecticides at mosquito muscarinic acetylcholine receptors to reduce malaria transmission
Role: Principal Investigator
Funding: VIRGINIA POLYTECHNIC INST AND STATE UNIV
via NATL INST OF HLTH NIAID
Nov 2020
– Aug 2021
Novel Spatial Repellents and Insecticides to Circumvent Pyrethroid Resistance
Role: Principal Investigator
Funding: US DEPT OF AG AG RES SVC
via ARMED FORCES PEST MANAGEMENT BOARD
Oct 2019
– Aug 2020
Novel Spatial Repellents and Insecticides to Circumvent Pyrethroid Resistance
Role: Principal Investigator
Funding: US DEPT OF AG AG RES SVC
via ARMED FORCES PEST MANAGEMENT BOARD
Jul 2019
– Nov 2020
Mode of Action of two Insecticidal Peptides and a Synthetic Analog
Role: Principal Investigator
Funding: VESTARON CORPORATION
Aug 2018
– Aug 2019
Novel Spatial Repellents and Insecticides to Circumvent Pyrethroid Resistance
Role: Principal Investigator
Funding: US DEPT OF AG AG RES SVC
via US ARMY
Jun 2018
ACTIVE
CAMTech IUCRC Phase II Memberships
Role: Project Manager
Funding: MULTIPLE SPONSORS
Dec 2016
– Jun 2022
Southeastern Regional CoE in Vector-Borne Diseases: The Gateway Program
Role: Co-Investigator
Funding: CTRS FOR DISEASE CONTROL AND PREVENTION
Aug 2015
– Aug 2016
Acquistion of Goods and Services
Role: Principal Investigator
Funding: US DEPT OF AG AG RES SVC
Feb 2015
– Feb 2020
Discovery and Development of New Public Health Pesticides
Role: Principal Investigator
Funding: US DEPT OF AG AG RES SVC
Aug 2014
– Aug 2018
Synthesis of Novel Insecticides using Structure-Activity Guided Design
Role: Principal Investigator
Funding: US DEPT OF AG AG RES SVC
Contact Details
Phones:
- Business:
- (352) 273-9417
Emails:
- Business:
- jbquist@ufl.edu
Addresses:
- Business Mailing:
-
EMERGING PATHOGENS INSTITTUE
GAINESVILLE FL 326110001