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Fungal Infections

Clinical and pathological characterization of Central Nervous System cryptococcosis in an experimental mouse model of stereotaxic intracerebral infection

Infection of the Central Nervous System (CNS) by the encapsulated fungus Cryptococcus neoformans can lead to high mortality meningitis, most commonly in immunocompromised patients. While the mechanisms by which the fungus crosses the blood-brain barrier to initiate infection in the CNS are well recognized, there are still substantial unanswered questions about the disease progression once the fungus is established in the brain.

Eggplant’s newest pathogenic fungus

A known pathogenic fungus, so far only reported to cause disease in two crops, has ensnared a third victim: eggplants. UF plant pathologists affiliated with both UF’s Institute of Food and Agricultural Sciences and the EPI, were the first to describe Lasiodiplodia hormozganensis’s jump to a new host.

Wilting Away

Plant pathology researchers with UF’s Emerging Pathogens Institute and IFAS seek to uncover what drives the spread of laurel wilt disease, an emerging forest pathogen responsible for killing more than 300 million redbays. A new study led by IFAS-EPI postdoctoral researcher Robin Choudhury found that the biggest indicator of a Laurel family trees’ susceptibility was having a large diameter trunk and dense clustering.