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New tuberculosis drug regimen slashes treatment time

Tuberculosis is an age-old respiratory scourge, with a new twist: growing resistance to multiple first- and second-line drugs. UF researchers and physicians report on using a novel treatment to slash treatment time — and cure — a patient with extensively drug-resistant TB.

Tuberculosis: it’s not the clone wars

Whole genome sequencing allows researchers to quantify diversification of Mycobacterium tuberculosis within a host, showing that the individual bacteria comprising an infection are not all identical clones. Using a known TB cluster, Emerging Pathogens Institute researchers confirm that hosts can transmit all — or just some — of the genetic diversity unique to their mTB population to a new victim.