Michael H Norris,
AFFL AST PROF
Teaching Profile
Courses Taught
2022-2023
GEO6938 Selected Topics in Geography
2023
GEO3930 Special Topics
2023
GEO4911 Undergraduate Research in Geography
2023
GEO4938 Selected Topics in Geography
Research Profile
Open Researcher and Contributor ID (ORCID)
0000-0002-5285-0432
Publications
2023
An investigation of the seasonal relationships between meteorological factors, water quality, and sporadic cases of Legionnaires’ disease in Washington, DC.
Epidemiology and infection.
151
[DOI] 10.1017/S0950268823000651.
[PMID] 37183701.
2023
Beyond the spore, the exosporium sugar anthrose impacts vegetative Bacillus anthracis gene regulation in cis and trans.
Scientific reports.
13(1)
[DOI] 10.1038/s41598-023-32162-x.
[PMID] 36977718.
2023
Excess mortality in Ukraine during the course of COVID-19 pandemic in 2020-2021.
Scientific reports.
13(1)
[DOI] 10.1038/s41598-023-33113-2.
[PMID] 37106001.
2023
Genomic and Phylogenetic Analysis of Bacillus cereus Biovar anthracis Isolated from Archival Bone Samples Reveals Earlier Natural History of the Pathogen
Pathogens.
12(8)
[DOI] 10.3390/pathogens12081065.
[PMID] 37624025.
2023
Sigma Receptor Ligands Prevent COVID Mortality In Vivo: Implications for Future Therapeutics
International Journal of Molecular Sciences.
24(21)
[DOI] 10.3390/ijms242115718.
[PMID] 37958703.
2023
Spatial and phylogenetic patterns reveal hidden infection sources of Bacillus anthracis in an anthrax outbreak in Son La province, Vietnam.
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases.
114
[DOI] 10.1016/j.meegid.2023.105496.
[PMID] 37678701.
2022
An Investigation of Burkholderia pseudomallei Seroprevalence in Market Pigs Slaughtered at Selected Pig Abattoirs in Uganda
Pathogens.
11(11)
[DOI] 10.3390/pathogens11111363.
[PMID] 36422614.
2022
Characterization of Bacillus anthracis replication and persistence on environmental substrates associated with wildlife anthrax outbreaks
PLOS ONE.
17(9)
[DOI] 10.1371/journal.pone.0274645.
[PMID] 36129912.
2022
Genome-scale CRISPR screens identify host factors that promote human coronavirus infection.
Genome medicine.
14(1)
[DOI] 10.1186/s13073-022-01013-1.
[PMID] 35086559.
2022
Low-frequency variants in mildly symptomatic vaccine breakthrough infections presents a doubled-edged sword.
Journal of medical virology.
94(7):3192-3202
[DOI] 10.1002/jmv.27726.
[PMID] 35307848.
2021
Combating Multidrug-Resistant Bacteria by Integrating a Novel Target Site Penetration and Receptor Binding Assay Platform Into Translational Modeling.
Clinical pharmacology and therapeutics.
109(4):1000-1020
[DOI] 10.1002/cpt.2205.
[PMID] 33576025.
2021
Correction: Convergent evolution of diverse Bacillus anthracis outbreak strains toward altered surface oligosaccharides that modulate anthrax pathogenesis.
PLoS biology.
19(2)
[DOI] 10.1371/journal.pbio.3001112.
[PMID] 33556066.
2021
Highly Specific Sigma Receptor Ligands Exhibit Anti-Viral Properties in SARS-CoV-2 Infected Cells
Pathogens.
10(11)
[DOI] 10.3390/pathogens10111514.
[PMID] 34832669.
2021
Identification of a PadR-type regulator essential for intracellular pathogenesis of Burkholderia pseudomallei.
Scientific reports.
11(1)
[DOI] 10.1038/s41598-021-89852-7.
[PMID] 34001967.
2021
Identification of antiviral antihistamines for COVID-19 repurposing
Biochemical and Biophysical Research Communications.
538:173-179
[DOI] 10.1016/j.bbrc.2020.11.095.
[PMID] 33309272.
2021
The Burkholderia pseudomallei intracellular ‘TRANSITome’
Nature Communications.
12(1)
[DOI] 10.1038/s41467-021-22169-1.
[PMID] 33772012.
2020
Convergent evolution of diverse Bacillus anthracis outbreak strains toward altered surface oligosaccharides that modulate anthrax pathogenesis
PLOS Biology.
18(12)
[DOI] 10.1371/journal.pbio.3001052.
[PMID] 33370274.
2020
Distribution of Serological Response to Burkholderia pseudomallei in Swine from Three Provinces of Vietnam
International Journal of Environmental Research and Public Health.
17(14)
[DOI] 10.3390/ijerph17145203.
[PMID] 32708490.
2020
Humoral Immune Responses to Burkholderia pseudomallei Antigens in Captive and Wild Macaques in the Western Part of Java, Indonesia
Veterinary Sciences.
7(4)
[DOI] 10.3390/vetsci7040153.
[PMID] 33050516.
2020
Laboratory strains of Bacillus anthracis lose their ability to rapidly grow and sporulate compared to wildlife outbreak strains
PLOS ONE.
15(1)
[DOI] 10.1371/journal.pone.0228270.
[PMID] 31978128.
2020
Nucleotide polymorphism assay for the identification of west African group Bacillus anthracis: a lineage lacking anthrose.
BMC microbiology.
20(1)
[DOI] 10.1186/s12866-019-1693-2.
[PMID] 31910798.
2020
Raxibacumab: a panacea for anthrax disease?
The Lancet. Infectious diseases.
20(8):886-887
[DOI] 10.1016/S1473-3099(20)30164-X.
[PMID] 32333846.
2020
TaqMan Assays for Simultaneous Detection of Bacillus anthracis and Bacillus cereus biovar anthracis
Pathogens.
9(12)
[DOI] 10.3390/pathogens9121074.
[PMID] 33371332.
2019
An in situ high-throughput screen identifies inhibitors of intracellular Burkholderia pseudomallei with therapeutic efficacy.
Proceedings of the National Academy of Sciences of the United States of America.
116(37):18597-18606
[DOI] 10.1073/pnas.1906388116.
[PMID] 31439817.
2019
Burkholderia pseudomallei acquired ceftazidime resistance due to gene duplication and amplification
International Journal of Antimicrobial Agents.
53(5):582-588
[DOI] 10.1016/j.ijantimicag.2019.01.003.
2019
Linking Geospatial and Laboratory Sciences to Define Mechanisms behind Landscape Level Drivers of Anthrax Outbreaks
International Journal of Environmental Research and Public Health.
16(19)
[DOI] 10.3390/ijerph16193747.
[PMID] 31590291.
2018
Lipid A Remodeling Is a Pathoadaptive Mechanism That Impacts Lipopolysaccharide Recognition and Intracellular Survival of Burkholderia pseudomallei.
Infection and immunity.
86(10)
[DOI] 10.1128/IAI.00360-18.
[PMID] 30037795.
2018
Outer Membrane Vesicle Vaccines from Biosafe Surrogates Prevent Acute Lethal Glanders in Mice.
Vaccines.
6(1)
[DOI] 10.3390/vaccines6010005.
[PMID] 29320408.
2018
Seroepidemiology of Burkholderia pseudomallei, Etiologic Agent of Melioidosis, in the Ouest and Sud-Est Departments of Haiti.
The American journal of tropical medicine and hygiene.
99(5):1222-1228
[DOI] 10.4269/ajtmh.18-0352.
[PMID] 30226137.
2018
Transcriptional and post-transcriptional regulation of PenA β-lactamase in acquired Burkholderia pseudomallei β-lactam resistance.
Scientific reports.
8(1)
[DOI] 10.1038/s41598-018-28843-7.
[PMID] 30006637.
2017
An avirulent Burkholderia pseudomallei ∆purM strain with atypical type B LPS: expansion of the toolkit for biosafe studies of melioidosis.
BMC microbiology.
17(1)
[DOI] 10.1186/s12866-017-1040-4.
[PMID] 28592242.
2017
Burkholderia pseudomallei natural competency and DNA catabolism: Identification and characterization of relevant genes from a constructed fosmid library.
PloS one.
12(12)
[DOI] 10.1371/journal.pone.0189018.
[PMID] 29253888.
2017
Development of Immunoassays for Burkholderia pseudomallei Typical and Atypical Lipopolysaccharide Strain Typing.
The American journal of tropical medicine and hygiene.
96(2):358-367
[DOI] 10.4269/ajtmh.16-0308.
[PMID] 27994103.
2017
Spatial transcriptomes within the Pseudomonas aeruginosa biofilm architecture.
Molecular microbiology.
106(6):976-985
[DOI] 10.1111/mmi.13863.
[PMID] 29030956.
2017
Structural diversity of Burkholderia pseudomallei lipopolysaccharides affects innate immune signaling.
PLoS neglected tropical diseases.
11(4)
[DOI] 10.1371/journal.pntd.0005571.
[PMID] 28453531.
2015
Single prokaryotic cell isolation and total transcript amplification protocol for transcriptomic analysis.
Nature protocols.
10(7):974-84
[DOI] 10.1038/nprot.2015.058.
[PMID] 26042386.
2014
Blocking phosphatidylcholine utilization in Pseudomonas aeruginosa, via mutagenesis of fatty acid, glycerol and choline degradation pathways, confirms the importance of this nutrient source in vivo.
PloS one.
9(7)
[DOI] 10.1371/journal.pone.0103778.
[PMID] 25068317.
2013
Elucidating the Pseudomonas aeruginosa fatty acid degradation pathway: identification of additional fatty acyl-CoA synthetase homologues.
PloS one.
8(5)
[DOI] 10.1371/journal.pone.0064554.
[PMID] 23737986.
2011
Knockout and pullout recombineering for naturally transformable Burkholderia thailandensis and Burkholderia pseudomallei.
Nature protocols.
6(8):1085-104
[DOI] 10.1038/nprot.2011.346.
[PMID] 21738123.
2011
The Burkholderia pseudomallei Δasd mutant exhibits attenuated intracellular infectivity and imparts protection against acute inhalation melioidosis in mice.
Infection and immunity.
79(10):4010-8
[DOI] 10.1128/IAI.05044-11.
[PMID] 21807903.
2011
Transcript amplification from single bacterium for transcriptome analysis.
Genome research.
21(6):925-35
[DOI] 10.1101/gr.116103.110.
[PMID] 21536723.
2010
Multiple FadD acyl-CoA synthetases contribute to differential fatty acid degradation and virulence in Pseudomonas aeruginosa.
PloS one.
5(10)
[DOI] 10.1371/journal.pone.0013557.
[PMID] 21042406.
2010
Stable, site-specific fluorescent tagging constructs optimized for burkholderia species.
Applied and environmental microbiology.
76(22):7635-40
[DOI] 10.1128/AEM.01188-10.
[PMID] 20851961.
2009
Engineering of tellurite-resistant genetic tools for single-copy chromosomal analysis of Burkholderia spp. and characterization of the Burkholderia thailandensis betBA operon.
Applied and environmental microbiology.
75(12):4015-27
[DOI] 10.1128/AEM.02733-08.
[PMID] 19376905.
2009
Glyphosate resistance as a novel select-agent-compliant, non-antibiotic-selectable marker in chromosomal mutagenesis of the essential genes asd and dapB of Burkholderia pseudomallei.
Applied and environmental microbiology.
75(19):6062-75
[DOI] 10.1128/AEM.00820-09.
[PMID] 19648360.
Grants
Nov 2021
– Dec 2022
PIADC 257 Decontamination Planning & Strategy
Role: Co-Project Director/Principal Investigator
Funding: MERRICK & COMPANY
via US DEPT OF HOMELAND SECURITY
Sep 2021
ACTIVE
Virulence and Protective Efficacy of Vaccines Against Antigenically Novel Bacillus anthracis Strains
Role: Project Manager
Funding: DEFENSE THREAT REDUCTION AGENCY
Jun 2021
– Jun 2022
An investigation of Burkholderia pseudomallei seroprevalence in market swine slaughtered at selected pig slaughterhouses in Uganda
Role: Principal Investigator
Funding: CORNELL UNIV
Aug 2020
– Nov 2022
TD-O4-013 Anthrax Surveillance in The Northern Philippines (Twin)
Role: Other
Funding: LEIDOS
via DEFENSE THREAT REDUCTION AGENCY
Jul 2019
– Feb 2021
STEP IDIQ Technical Directive TD-O2-003 Vietnam Melioidosis Research Preparedness Part II
Role: Project Manager
Funding: LEIDOS
via DEFENSE THREAT REDUCTION AGENCY
Sep 2018
– May 2019
Technical Directive TD-O1-011: Vietnam Melioidosis Research Preparedness
Role: Project Manager
Funding: LEIDOS
via DEFENSE THREAT REDUCTION AGENCY
Contact Details
Phones:
- Business:
- (352) 273-8445
Emails:
- Business:
- mhnorris@ufl.edu
Addresses:
- Business Mailing:
-
PO Box 117315
GAINESVILLE FL 32611 - Business Street:
-
3414 Turlington Hall
GAINESVILLE FL 32611