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Exploring diversity of bacterial spot associated Xanthomonas population of pepper in Southwest Florida

Bacterial spot caused by spp. is a significant disease that challenges pepper growers worldwide and is particularly severe in a hot and humid environment. Understanding the pathogen’s population biology is critical for sustainable disease management. The goal of this study was to characterize the species, race, and bactericide sensitivity of bacterial spot-associated Xanthomonas collected from pepper in Florida.

Strength in Numbers: Density-Dependent Volatile-Induced Antimicrobial Activity by Xanthomonas perforans

For most of the 20th century, Xanthomonas euvesicatoria was the only known bacterium associated with bacterial spot of tomato in Florida. X. perforans quickly replaced X. euvesicatoria, mainly because of production of three bacteriocins (BCNs) against X. euvesicatoria; however, X. perforans outcompeted X. euvesicatoria even when the three known BCNs were deleted. Surprisingly, we observed antimicrobial activity against X. euvesicatoria in the BCN triple mutant when the triple mutant was grown in Petri plates containing multiple spots but not in Petri plates containing only one spot.

Pretomanid-resistant tuberculosis

An individualized intensified treatment with high-dose therapy was initiated and weekly monitoring of TTP, regular pDST and minimal inhibitory concentration (MIC) testing in mycobacteria growth indicator tubes (MGIT), gDST by whole-genome sequencing (WGS), TDM and electro-cardiographic (ECG) monitoring of the QTc-interval were performed. Drug concentrations were compared to reference values and observational studies

New tuberculosis drug regimen slashes treatment time

Tuberculosis is an age-old respiratory scourge, with a new twist: growing resistance to multiple first- and second-line drugs. UF researchers and physicians report on using a novel treatment to slash treatment time — and cure — a patient with extensively drug-resistant TB.

UF study reveals how Chlamydia acquires essential nutrients

New work from the lab of Tony Maurelli, associate chair of the department of environmental and global health in UF's College of Public Health and Health Professions, has solved a quirky mystery about parasitic bacteria that cause the sexually-transmitted disease known as Chlamydia.

Next-Gen antimicrobials

EPI investigator KC Jeong aims to uncover the next generation of antimicrobials. From his microbiology lab to an experimental farm, his research explores how food animals are affected by novel and drug-resistant pathogens — and what kills them.

Grazing cows acquire antibiotic resistant microbes from soil, water

An Emerging Pathogens Institute microbiologist has identified high concentrations of naturally-occurring antibiotic-resistant microbes within the guts of grazing cows and calves fed a diet free from antibiotics. The source? Soil, water and forage found in the cows’ environment.