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Genetics

Vibrio cholerae Invasion Dynamics of the Chironomid Host Are Strongly Influenced by Aquatic Cell Density and Can Vary by Strain

Cholera has been a human scourge since the early 1800s and remains a global public health challenge, caused by the toxigenic strains of the bacterium Vibrio cholerae. In its aquatic reservoirs, V. cholerae has been shown to live in association with various arthropod hosts, including the chironomids, a diverse insect family commonly found in wet and semiwet habitats.

Rui Chen wins the early-stage investigator poster competition

Postdoctoral candidate Rui Chen won best research poster in the EPI Research Day 2023 Early-Stage Investigator Poster Competition. Her poster consisted of several interrelated projects, but her main research focused on characterizing the function of inwardly rectifying potassium (Kir) channels in insects nervous system.  

Research day recap: responding to COVID in South Africa and Senegal

The Emerging Pathogens Institute’s annual Research Day event celebrates pathogens research and the people who work in this critical academic space. After three years of meeting virtually, the event was held in person at the Reitz Union on Feb. 16, 2023 on the University of Florida’s campus. Researchers and students exhibited 123 abstracts and posters that probed pathogens and infectious diseases topics spanning from lab research to field investigations and bioinformatic analyses.

Effects of partially replacing dietary corn with sugars in a dual-flow continuous culture system on the ruminal microbiome

The objective of this study was to evaluate the effects of feeding sugars as a replacement for starch on the ruminal microbiome using a dual-flow continuous culture system. Four periods of 10 days each were conducted with 8 fermenters in a 4 × 4 replicated Latin square design. Treatments included: 1) control with corn—CON, 2) molasses—MOL, 3) untreated condensed whey permeate—CWP, and 4) CWP treated with a caustic agent—TCWP as a partial substitute for corn.

Pseudohepatospora borealis n. gen. n. sp. (Microsporidia: Enterocytozoonida): a microsporidian pathogen of the Jonah crab (Cancer borealis)

The microsporidian diversity catalogued so far has resulted in the development of several taxonomic groups, one of which is the Enterocytozoonida – a group of generalist ‘ultimate opportunists’, which infect many fished and aquacultured animals, as well as a broad suite of host taxa, including humans. In this study, we provide phylogenetic, ultrastructural, developmental, and pathological evidence for the creation of a new genus and species to hold a microsporidian parasite of the Jonah crab, Cancer borealis.

Research day recap

From land to sea, EPI’s Research Day keynote talks featured recent leaps in pathogen research affecting people and the aquatic animal source foods we consume.

Harnessing genome editing for Covid-19 drug discovery

A plaque, or area of destroyed cells in a cell culture shows the presence of an active SARS-CoV-2 infection. (Image courtesy of Mike Norris) A University of Florida research team is harnessing the power of genomic editing to illuminate druggable targets in human cells for the fight against…