Candida albicans is a leading cause of life-threatening invasive infection despite antifungal therapy. Patients with chronic liver disease are at increased risk of candidemia, but the mechanisms underlying this susceptibility are incompletely defined. One consequence of chronic liver disease is an attenuated ability to produce hepcidin and maintain organismal control of iron homeostasis.
Cholera remains a major and increasing global public health problem for all people without adequate access to safe water. Goma, in the eastern Democratic Republic of Congo (DRC), has been a major cholera hotspot in Africa since 1994 and is currently experiencing one of the largest outbreaks in the world.
Contact investigations are crucial for tuberculosis (TB) control, yet the temporal dynamics of disease progression among exposed contacts remain poorly understood. We conducted a retrospective cohort study of 44,106 contacts linked to 6,243 index TB cases diagnosed between 2009 and 2023.
Florida remains a high-incidence, high-prevalence setting for HIV. Long-acting (LA) antiretroviral therapies (ART) could improve HIV-related outcomes and reduce transmission. This study identifies preferred LA ART characteristics and classes of preference among persons with HIV (PWH) in Florida.
Plasmids are key drivers of horizontal gene transfer. These genetic elements promote diversification and rapid adaptation of bacterial populations to changing environments by transferring beneficial traits within and between bacterial species. Xanthomonas euvesicatoria pv. perforans is a devastating plant pathogen that causes bacterial spot disease in tomato and pepper.
Psyllids, also called plant lice, are hemipteran insects that feed on phloem sap. In addition to the direct damage they cause to plants, they are vectors of many phloem-restricted bacterial pathogens belonging to the ‘Candidatus Liberibacter’ spp. and ‘Candidatus Phytoplasma’ spp. from the apple proliferation group (16SrX). Although ‘Candidatus Liberibacter’ spp. cells possess cell walls unlike those of the phytoplasmas, they both share a reduced genome and unavailability in culture.
Previous studies have shown decreased microbial diversity in astronaut gut microbiomes during spaceflight, raising potential health concerns. Enterobacter cloacae, a commensal member of the human gastrointestinal tract microbiota, has the potential to cause opportunistic infections in immunocompromised patients.
This report describes the complete genome sequence of the non-bioluminescent marine bacterium Photobacterium piscicola strain WVL24019, isolated from a one-year freshwater hatchery-raised rainbow trout in a non-recirculating system supplied by aquiferous water. The genome was sequenced using Oxford Nanopore and Illumina NovaSeq technologies, resulting in two complete circular chromosomes.
Spirometra is a genus of zoonotic cestodes with an ambiguous species–level taxonomic history. Previously, Spirometra mansonoides was considered the only species present in North America. However, recent molecular data revealed the presence of at least three distinct species in the United States of America (USA): Spirometra sp. 2 and 3, and Spirometra mansoni.
Temperature shapes the geographic distribution, seasonality, and magnitude of mosquito-borne disease outbreaks. Models predicting transmission often use mosquito and pathogen thermal responses measured at constant temperatures. However, mosquitoes live in fluctuating temperatures.
